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Galleri: Understanding a Cancer Signal Detected Result

There are two possible Galleri test results: No Cancer Signal Detected Cancer Signal Detected In this video, we will review what a Cancer Signal Detected result means. If you received a Cancer Signal Detected result, the Galleri test detected DNA fragments associated with cancer in your blood sample. About 1 out of every 100 tests has a Cancer Signal Detected result.1* This result will also include a prediction of the tissue type or organ associated with the cancer signal, called a ​Cancer Signal Origin (CSO). This provides direction to your doctor on the cancer’s origin and can help guide the next steps for diagnosis.2* In a clinical study, around 4 out of 10 people with this result were diagnosed with cancer after diagnostic testing.1 The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. The Galleri test should be used in addition to healthcare provider recommended screening tests. Learn more about the Galleri test: https://www.Grail.com https://www.Galleri.com Rx only. See Important Safety Information: https://www.Galleri.com/safety References *[GRAIL, Inc. Data on file: VV-TMF-59592] 1. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402:1251-1260. doi: 10.1016/S0140-6736(23)01700-2 2.Klein EA, Richards D, Cohn A, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806