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NSAIDs EXPLAINED: Selective vs. Non-Selective COX Inhibitors (USMLE High-Yield Pharmacology)

💊 NSAIDs: Selective vs. Non-Selective COX Inhibitors Explained (Pharmacology Review) Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) are a widely used class of medications that inhibit cyclooxygenase (COX) enzymes to reduce pain, inflammation, and fever. But how do COX-1 and COX-2 inhibitors differ, and what are their clinical implications? This video provides a high-yield breakdown of NSAID pharmacology, COX inhibition mechanisms, indications, side effects, and USMLE-relevant concepts—perfect for medical students, USMLE prep, and healthcare professionals. What You’ll Learn in This Video: ✔️ Mechanism of Action: How NSAIDs inhibit COX-1 & COX-2 enzymes ✔️ Non-Selective NSAIDs (COX-1 & COX-2 Inhibitors): Ibuprofen, Naproxen, Aspirin, Indomethacin ✔️ Selective COX-2 Inhibitors: Celecoxib & why they reduce GI side effects ✔️ Clinical Indications: Pain management, inflammation, cardiovascular protection ✔️ Side Effects & Risks: GI ulcers, renal toxicity, cardiovascular risks ✔️ Aspirin vs. Other NSAIDs: Why aspirin is cardioprotective ✔️ High-yield mnemonics & USMLE exam pearls ⏰ Timestamps for Easy Navigation: 0:00 Classification of NSAID’s 0:55 The role of PG’s in normal condition 2:32 The effect of non-selective NSAID’s 4:55 The effect of selective NSAID’s 6:33 Summary 💡 Engage With Us: Question for You: Which NSAID do you think has the best safety profile? Drop your thoughts in the comments! Don’t forget to like 👍 this video, subscribe 🔔 to the channel, and share this with fellow students & professionals! https://t.me/foxterRier_med #usmle #step1 #step2 #medicine #pathology #physiology #education #medicalschool #pharmacology #biochemistry #highyield #lab