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Prof. Tuomas Knowles - Protein self-assembly – understanding and controlling the machinery of life

Proteins are the active molecules of life. However, most proteins do not work on their own in health or disease; a key challenge, therefore, is understanding how these molecules interact with each other to give rise to function or malfunction. This talk will outline our efforts to discover, understand and use the basic principles that drive protein assembly into larger scale structures and phases. I will discuss how controlling transitions between such phases can help us ameliorate biological malfunction when it occurs in disease, and well as develop new classes of functional materials.