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Pulmonary Artery Hypertension | Clinical Medicine 2 месяца назад


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Pulmonary Artery Hypertension | Clinical Medicine

Premium Member Resources: https://www.ninjanerd.org/lectures/pu... Ninja Nerds! Professor Zach Murphy will be presenting on Pulmonary Artery Hypertension (PAH). We will be going into detail on the following main objectives: 1. Definition and Classification of Pulmonary Artery Hypertension - Understand what pulmonary artery hypertension (PAH) is and how it differentiates from other types of hypertension. - Familiarize yourself with the World Health Organization (WHO) functional classification system, which categorizes PAH based on symptom severity and limitations in daily activities. 2. Pathophysiology and Etiologies - Delve into the underlying mechanisms that contribute to PAH, including vasoconstriction, vascular remodeling, and inflammation. - Examine the role of various risk factors such as genetics, connective tissue diseases, and drug exposures in the onset and progression of PAH. 3. Clinical Manifestations and Presentation - Learn to identify the common signs and symptoms associated with PAH, including but not limited to dyspnea, fatigue, and chest pain. - Discuss the markers of disease severity and progression, such as exercise intolerance and the occurrence of syncope. 4. Diagnostic Criteria and Tools - Understand the utility and interpretation of diagnostic tests like echocardiography, right heart catheterization, and pulmonary function tests. - Familiarize yourself with the latest guidelines and consensus criteria for diagnosing PAH. 5. Initial Management Strategies - Discuss evidence-based approaches for initial patient stabilization, focusing on pharmacotherapy with agents like endothelin receptor antagonists and phosphodiesterase-5 inhibitors. - Understand the indications for supportive measures like oxygen therapy and diuretics. 6. Definitive Management Approaches - Explore advanced treatment options such as prostacyclin analogs, soluble guanylate cyclase stimulators, and surgical interventions like lung transplantation. - Evaluate the risks and benefits of each management strategy in light of the most current research and guidelines. 7. Complications and Prognosis - Understand the potential complications of PAH, including right ventricular failure and arrhythmias. - Discuss prognostic factors that can influence long-term outcomes, including WHO functional class, exercise capacity, and hemodynamic parameters. Table of Contents: 0:00 Lab 0:07 Pulmonary Artery Hypertension (PAH) Introduction 0:37 Pathophysiology | Type I PAH 3:37 Pathophysiology | Type II PAH 5:39 Pathophysiology | Type III PAH 7:29 Pathophysiology | Type IV PAH 8:55 Complications | Right Heart Failure 13:17 Diagnostic Approach 17:26 Treatment 17:53 Vasodilator Therapy 19:52 Comment, Like, SUBSCRIBE! Retired Ninja Nerd Lectures:    • Pulmonary Hypertension | Retired   Ninja Nerd Website | https://ninjanerd.org Ninja Nerd Podcast | https://podcast.ninjanerd.org Ninja Nerd Store | https://merch.ninjanerd.org   / ninjanerdlectures     / ninjanerdlectures     / ninjanerdlectures     / @ninjanerdsci     / discord   #ninjanerd #respiratory #pulmonaryhypertension

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