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The Nose Knows: How Smell Triggers Memories

This video delves into the process of how smell is capable of eliciting vivid and emotional memories, also known as odor evoked autobiographical memory. Follow along as odor molecules travel into the nasal cavity where they are converted into electrical signals. Then hop on for the ride as these electrical signals are sent to the brain to various parts of the brain—including a fascinating route to memory structures where they become linked to memories. This video was made by McMaster students Naya Nour-Eddin, Crystal Chen, Haleh Hojjati, and Amna Usmani in collaboration with the McMaster Demystifying Medicine Program. Copyright McMaster University 2021 References: Araneda, R. C., Kini, A. D., & Firestein, S. (2000). The molecular receptive range of an odorant receptor. Nature Neuroscience, 3(12), 1248–1255. https://doi.org/10.1038/81774 Cutsuridis, V., & Yoshida, M. (2017). Editorial: Memory Processes in Medial Temporal Lobe: Experimental, Theoretical and Computational Approaches. Frontiers in Systems Neuroscience, 11, 19. https://doi.org/10.3389/fnsys.2017.00019 Glachet, O., & El Haj, M. (2019). Emotional and Phenomenological Properties of Odor-Evoked Autobiographical Memories in Alzheimer’s Disease. Brain Sciences, 9(6), 135. https://doi.org/10.3390/brainsci9060135 Kadohisa, M. (2013). Effects of odor on emotion, with implications. Frontiers in Systems Neuroscience, 7, 66. https://doi.org/10.3389/fnsys.2013.00066 Sharma, A., Kumar, R., Aier, I., Semwal, R., Tyagi, P., & Varadwaj, P. (2019). Sense of Smell: Structural, Functional, Mechanistic Advancements and Challenges in Human Olfactory Research. Current Neuropharmacology, 17(9), 891–911. https://doi.org/10.2174/1570159X17666... Scientific diagrams created on Biorender.com