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Cold Agglutinin Disease Animation - Mechanism of Disease

Cold agglutinin disease, (CAD), is a rare form of autoimmune hemolytic anemia, where the body mistakenly recognizes the antigens on the surface of red blood cells as foreign. This leads to extravascular and intravascular hemolysis, and a range of severe symptoms, including acrocyanosis, extreme fatigue, dyspnea and hemoglobinuria. The objective of the animation was to help educate Health Care Professionals on the mechanism of disease for cold agglutinin disease. The animation was used at The American Society of Hematology and is now featured on the Sanofi Genzyme disease education website, understandingcad.com. This animation has won 9 industry awards for the quality of animation.