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Patrik Rorsman: Diabetes and Insulin Secretion

Islet hormones and Insulin secretion Prof. Patrik Rorsman studies the fundamental processes which control insulin secretion under physiological conditions and determine the defects associated with clinical diabetes. His work involves a number of techniques which look at the secretion of insulin, glucagon and somatostatin at molecular, cellular and systemic levels. Type-2 Diabetes The details of type-2 diabetes are unclear; we think there is a problem with the pancreatic beta cells which produce electrical signals to instigate insulin secretion. By working with human (rather than rodent) cells we are hoping to eventually develop new diabetes medicines, and in the short term make better beta cells available for transplantation.