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What is Subunit Vaccine?

Subunit vaccines are a type of next-generation vaccine that focus on using specific parts of the pathogen instead of the whole organism. A subunit vaccine utilizes specific components or subunits of a pathogen to stimulate an immune response in the body. Unlike traditional vaccines that may contain weakened or inactivated forms of the entire pathogen, subunit vaccines focus on using key proteins, peptides, or carbohydrates of microorganism that are responsible for triggering the immune system's response. There are several methods to create subunit vaccines, each with its own advantages and considerations. Here are some commonly used methods: Recombinant DNA technology: This method involves genetically engineering a host organism, such as bacteria or yeast, to produce the desired subunit of the pathogen. The host organism is modified to express the protein or peptide subunit, which can then be harvested and purified for use in the vaccine. Protein purification: In this method, the subunit proteins or peptides are isolated and purified directly from the pathogen or produced using recombinant DNA technology. This process typically involves breaking down the pathogen, separating the desired subunits, and purifying them to remove any unwanted components. Synthetic peptide synthesis: Synthetic peptides can be chemically synthesized in the laboratory to mimic specific subunits of a pathogen. These synthetic peptides can then be formulated into a vaccine. The purpose of subunit vaccines is to stimulate an immune response in the body against a specific pathogen or infectious agent. By using specific components or subunits of the pathogen, subunit vaccines can trigger the immune system's recognition and memory of the pathogen without causing the actual disease. There are several examples of subunit vaccines that have been developed and widely used. Some notable examples include: Hepatitis B vaccine: The hepatitis B vaccine is a well-known subunit vaccine. It contains a subunit of the hepatitis B virus called the hepatitis B surface antigen (HBsAg). By administering this subunit, the vaccine stimulates the immune system to produce antibodies against the HBsAg, providing protection against hepatitis B infection. Human papillomavirus (HPV) vaccine: The HPV vaccine is a subunit vaccine that targets specific proteins from the human papillomavirus. The vaccine contains one or more of the viral proteins, such as the major capsid protein L1. HPV vaccines protect against certain strains of HPV that are responsible for causing cervical cancer, as well as other types of cancers and genital warts. For more detail kindly go through the video and don't forget to subscribe my channel ‪@tinypredators‬ Thank you!! #what is subunit vaccine define subunit vaccine #rDNA Protein purification Synthetic peptide synthesis Virus-like particle Conjugation purpose of subunit vaccines Hepatitis B vaccine Acellular pertussis vaccine Meningococcal conjugate vaccines COVID-19 vaccines HPV vaccines use of vaccines disease eradication vaccination child immunization prevention of disease Immune response antigen antibody B cells T cells macrophages CD4 CD8 vaccine dose vaccine route #baayo #biology with aagam singh #shomu's biology #basic & applied microbiology classes #microbiology with sumi #MLT education point #quick support #Dr sonu panwar NEET to next infectious diseases #tiny Predators For more video like this kindly subscribe my channel @tinypredators Thank you....