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Top data from ESOC 2022: ATTENTION, AcT, and TASTE-A

Raul Nogueira, MD, University of Pittsburgh, Pittsburgh, PA, comments on several major highlights from the European Stroke Organisation Conference 2022, highlighting data that is likely to be practice changing. The ATTENTION trial (NCT04751708) was a multicenter, randomized controlled clinical trial investigating the use of endovascular treatment compared to best medical management (BMM) for patients with acute ischemic stroke with basilar artery occlusion. Strongly positive results were presented at the meeting, with favorable outcomes (modified Rankin scale score of 0-3) seen in 46% versus 24% in the thrombectomy and BMM arms, respectively, giving a number needed to treat of 4. Additionally, several trials were presented looking at the use of tenecteplase for intravenous thrombolysis. Data suggested tenecteplase was as, if not more, efficacious than alteplase (AcT trial; NCT03889249), easier to use, and feasible in a mobile stroke unit setting (TASTE-A trial; NCT04071613). This interview took place at European Stroke Organisation Conference 2022 in Lyon, France.

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